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The current finding is in harmony with prior studies where RVX possessed an anti-oxidant effect in cisplatin-induced testicular damage 35 , renal injury induced by sunitinib 52 , and sunitinibinduced cardiotoxicity 53 .Oxidative stress results from the imbalance between the formation of ROS and anti-oxidants

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It is still unclear whether changes in microbiota directly cause changes in bile acids, whether bile acids have an effect on the microbiota, or whether both are outcomes of LT therapy

The full description of each category should be read on the FDAs website, but in short, materials listed in Category 1 may be used as bulk drug substances provided that all other relevant legal and regulatory conditions are met