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While not directly sleep-related, systemic inflammation is a well-established disruptor of sleep quality Autoimmune myocarditis (FASEB J, 2017) -- attenuation of disease via Treg generation, further establishing anti-inflammatory potential Structure-activity studies (Nature Communications, 2021) -- investigation of analogs with improved selectivity, suggesting potential future clinical development No human studies have been conducted for cortistatin in any indication, including sleep

250 mg Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide and Magnesium Stearate

Specifically, Melanotan has been found to bind with melanocortin receptors in the brain, which play crucial roles in regulating appetite and metabolism