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deubiquitinase glutathione

deubiquitinase glutathione Frontiers Structural insights into ubiquitin chain

Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases Life Science Alliance Ubiquitination and deubiquitination in cancer: from mechanisms to novel therapeutic approaches Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases PMC Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis ScienceDirect Deubiquitinases as novel therapeutic targets for diseases Xian 2024 MedComm Wiley Online Library

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Drug Des Methodol Concepts, Mode-of-Action

deubiquitinase glutathione Frontiers Structural insights into ubiquitin chain

Mitochondrial damage causes ATP depletion and ROS burst, exacerbating inflammation and disrupting the intestinal barrier

deubiquitinase glutathione Frontiers Structural insights into ubiquitin chain

J Pharmacol Sci 108:22738, PMID: 19008644 Lertratanangkoon K, Wu CJ, Savaraj N, Thomas ML (1997) Alterations of DNA methylation by glutathione depletion

deubiquitinase glutathione Frontiers Structural insights into ubiquitin chain

Retinol-binding protein 4 accelerates metastatic spread and increases impairment of blood flow in mouse mammary gland tumors

deubiquitinase glutathione Frontiers Structural insights into ubiquitin chain

For example, the FAO inhibitor etomoxir reversed cisplatin resistance in cisplatin-resistant cells from OC and GC [57, 64], perhexiline reversed AUY922 resistance in PCa cells [51], and thiolidazine reversed enzalutamide resistance in PCa cells [155]

deubiquitinase glutathione Frontiers Structural insights into ubiquitin chain
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