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Similarly, pharmacological inhibition of GPX4 by Ras-selective lethal compound 3 (RSL3) blocks the enzymatic detoxification of lipid hydroperoxides, resulting in excessive lipid peroxidation and ferroptotic cell death [56,57,58] (Fig

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Most studies and data focus on infertility in women, yet there has been relatively little attention given to the male contribution to infertility which may be a factor for more than half of infertile couples

Article search State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica

Like the approach used for the discovery cohort, we next searched for additional proteins that may be indicative of differences in the same cohort using (s)PLS-DA analysis