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However, the patient must also take into account that results may vary

Shao SC, Kuo LT, Huang YT, Lai PC, Chi CC: Using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to rate the certainty of evidence of study outcomes from systematic reviews: a quick tutorial

If the 4 mg maintenance arm proves non-inferior for weight maintenance in Phase 3, researchers may be able to titrate up to a high working dose during the active weight-loss phase, then step back down to a lower 4 mg maintenance dose for the long stabilization phase