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Edited by Alessandro Finazzi-Agr Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

Adv Pharm Bull 7(3):339 Liu CH et al (2017) Animal models of ocular angiogenesis: from development to pathologies

Via AMPK and SIRT1 signaling, melatonin enhances adiponectin and restrains leptin hypersecretion, improving metabolic flexibility (239)

Therefore, the average percentage of the ROS in the treated group on days 35 and 42 of the study, was 2.01% and 2.85%, respectively