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Marked reductions in bioactive insulin-like growth factor I (IGF-I) during hemodialysis

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What to do: Stop copper peptides Stop retinoids, AHAs, BHAs, vitamin C, and all other actives Use only gentle, fragrance-free cleanser Apply simple, barrier-repairing moisturizer Use mineral sunscreen (zinc oxide or titanium dioxide based) Products to use: Cleanser: Cetaphil Gentle Skin Cleanser, La Roche-Posay Toleriane, or similar Moisturizer: CeraVe Moisturizing Cream, Vanicream, or products with ceramides Sunscreen: EltaMD UV Physical, Blue Lizard Sensitive What to avoid: Hot water (use lukewarm only) Mechanical exfoliation (scrubs, brushes) Fragranced products Essential oils Any active ingredients Timeline: Stick with this minimal routine for 2 weeks minimum

overlay of the two fluorescent signals is shown in the third row

Matta et al., 2021)