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Kostick N, Chen E, Eckert T, Sirotkin I, Baldinger E, Frontera A

While 0 generally indicated no changes, the lesions were subsequently scored as follows: 0-3, edema (1- weak diffuse and/or perifocal

"Stability of protein pharmaceuticals: an update." Pharmaceutical Research, 27(4), 544575

The euchromatin is characterized by an open state and is amenable to transcription, while the heterochromatin is characterized by a compact DNA-protein structure that cannot be transcribed (Jenuwein and Allis, 2001)