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363 Reduced activity and expression of the GLUT-1 transporter in the BBB suggest decreased glucose uptake and utilization by the brain, 360,363 which may further exacerbate cerebrovascular degeneration, BBB breakdown, and A pathology in models overexpressing APP, inducing neurodegeneration and cognitive deficits (Fig

Using a modified three-step nanoprecipitation and self-assembly method, they developed Enzalutamide (ENZ)-loaded PLGA-NPs coated with polysarcosine and D--Tocopheryl polyethylene glycol 1000 succinate (TPGS)

Since NAC had no effect on Notch2 at 2 mM or 5 mM but attenuated Notch2 expression at 10 and 20 mM, we used high dose of NAC at 10 mM in most of following studies

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