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Understanding the mechanisms and drivers of antimicrobial resistance

Its not about keeping the water 'fresh' like a carton of milk

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Notably, the hypoxic environment of the periodontal pocket further synergistically upregulates TFRC by stabilizing hypoxia-inducible factor-1 (HIF-1) and enhancing the endocytosis of transferrin-bound ferric iron (Fe 3+ ) (11)