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This concern arises from the fact that studies of hGH have shown that long-term exogenous administration, while increasing lean body mass and decreasing adipose tissue, can also cause: increased insulin resistance, diabetes, acromegaly, cancer, hypertension (high blood pressure), and edema (swelling)

If inhibiting NAD+ synthesis has an adverse effect on 5-amino-1MQs muscle-enhancing effects, this would show that, indeed, the compound likely works through increasing NAD+ levels

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Research shows this compound affects multiple pathways at once, making it useful for comprehensive metabolic research.On the other hand research shows that 5 amino 1mq works through NNMT inhibition, giving scientists a different perspective on cellular energy regulation