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In the future, we will develop small molecule inhibitors or activators for specific transporters such as SLC25A39 and xCT, and use gene editing tools (such as CRISPR/Cas9) to precisely edit related genes to achieve precise regulation of GSH metabolism, providing more targeted means for disease treatment

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doi: 10.1111/j.1365-2605.2005.00598.x 31 DuttaSSenguptaPRoychoudhurySChakravarthiSWangCWSlamaP

Amino acid metabolism in cancer The uptake and metabolism of amino acids represent another critical metabolic pathway, in addition to glycolysis, that sustains the malignant growth of tumors

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