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A reduction in detoxification activity occurs when the deletion in gene GSTM1 is inherited, meaning that being a homozygous carrier of a deletion in the GSTM1 gene causes a reduction in enzyme activity

If you're wondering why you might have low homocysteine, here are common culprits: 1

The magnitude of these differences suggests that the benefits of dual agonism extend beyond simple additive effects

Topical estrogen in combination with any other bioidentical hormone that is compounded has not been shown to be more effective or safer than other hormone options, nor are they approved by the FDA for safety and efficacy