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As an alternative or additional function, we propose that the targeting of LRP6 to AP2-containing structures assists assembly of a signalosome by exposing its components to kinases that are co-targeted to these locales by AP2, and that these kinases could remodel the structure or activity of the signalosome by phosphorylating its components (Fig

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"[Effects of introduction of short peptides before carotid artery occlusion on behaviour and caspase-3 activity in the brain of old rats]"

Injection Site Selection For subcutaneous injections, common sites include the abdomen at least two inches from the navel, front and outer thighs, and back of upper arms