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While our study focused on endothelial K-Hcy-HMGB1/2-mediated senescence, K-Hcy modifications may constitute a novel pathological axis that disrupts multiple proteins and cellular processes, thereby driving ED through broader and previously unrecognized mechanisms

FUE (Follicular Unit Extraction) FUE involves removing individual hair follicles from the safe donor area (usually the back or sides of the head) using a small punch tool

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His groundbreaking observation showed that aged liver tissue could synthesize proteins like younger tissue when exposed to this compound