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A) Heinz bodies on peripheral smear B) Low lactate dehydrogenase C) Positive direct Coombs test D) Positive indirect Coombs test Answer: A Patients with glucose-6-phosphate dehydrogenase ( G6PD ) deficiency will have a low hemoglobin concentration level and Heinz bodies on peripheral smear when exposed to oxidative stress

Elevated iron levels promote ROS production, depleting intracellular GSH levels and accelerating lipid peroxidation

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Similarly, it has been observed that KRAS mutation induces activation of the glutamine metabolism pathway in pancreatic cancer by enhancing the expression of pivotal enzymes responsible for glutamine degradation [92]

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