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(2) body mass index (BMI) for male participants weighing 50 kg or more and female subjects weighing 45 kg or more, with BMI = weight/height 2 (kg/m 2 ), including borderline values

Like RO4929097, several other compounds that target important cellular signaling pathwayssuch as Notch, Wnt/-catenin, JAK/STAT, NF-B, Hedgehog, PI3K/Akt/mTOR, and TGF/SMADhave been shown to target CSCs in various cancer types [48,49,50]

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In this model a diet mixed with silymarin 0.5 % w/w (approx

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