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Supramolecular nanoparticle loaded with bilirubin enhances cartilage protection and alleviates osteoarthritis via modulating oxidative stress and inflammatory responses

On the contrary, in anemic conditions where the number of circulating RBCs is decreased without concomitant hemolysis, a decrease of RBC-dependent scavenging of NO may instead increase systemic NO bioavailability and cause vasodilation, increased flow, and may affect cardiovascular hemodynamics (140)

This in turn results in oxidative damage, lipid peroxidation, and cellular dysfunction

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These components are believed to increase the levels of GABA in the brain, a neurotransmitter that helps regulate nerve impulses and promote relaxation