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These genes are associated with tolerance to acid, osmotic, and bile stress in the stomach (Cotter et al., 2005

Li M, Sun P, Tu B, Deng G, Li D, He W

None of the QTc elevations were considered clinically relevant by Principal Investigators

Following injection in a mouse model, both 113-O12B and ALC-0315 exhibit noticeable drainage signals, with ALC-0315 showing significantly higher expression in the liver (Fig