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In a related study, exposure to Al was found to upregulate TGF- , thus inducing oxidative stress with an attendant increase in apoptosis-related protein expression and subsequent kidney cell apoptosis (35)

Investigating the gut and lung microbes from individuals with non-small cell lung cancer (NSCLC) and healthy individuals revealed an altered composition of both microbiota and an abundance of Pseudomonas aeruginosa in individuals with brain metastasis (164)