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Improper storage Leaving reconstituted peptides at room temperature significantly reduces stability

Silymarin scavenges reactive oxygen species (ROS) and increases the activity of endogenous antioxidant enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase, thereby mitigating oxidative damage in liver cells

In addition, higher-wash NaCl concentration at pH 8 and decreased NaCl concentration with 1 mM GSH at pH 8 resulted in improved serum protein clearance

Chandra V, Mahajan S, Saini A, Dkhar HK, Nanduri R, Raj EB, Kumar A, Gupta P

However, we acknowledge that a rigorous preclinical evaluation of Cur-NCs, including safety assessments such as acute and potential long-term toxicity studies, as well as pharmacodynamic investigations across various animal species, has yet to be conducted