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Description

NAPstar3b was chosen as due to its K r(NADPH/NADP+) we expected it to be almost fully NADPH bound at steady state, therefore allowing for the maximum possible deflection upon NADP oxidation, and due to its particularly low NADH binding affinity

ZhangTOConnorCSheridanHBarlowJW

Andreeff M , Giles F, Kornblau S, Konopleva M, Leysath C, Jackson CE, Edwards K, Ross B, Faldas M, Williams A, Estey E, Kantarjian H

The pharmaceutical formulation disclosed herein may comprise hydroxypropyl- alpha-cyclodextrin having a minimum of about 0.4 hydroxypropyls per glucose unit