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[DOI] [PMC free article] [PubMed] [Google Scholar] [25].Heinonen I, Laukkanen JA

Methodological consensus on clinical proton MRS of the brain: review and recommendations

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Presence of knee rOA or pain at Baseline was used to dichotomise individuals for predictive modelling, due to the previous similarities in molecular patterns between iOA and PTOA [17]

Although many other panels making clinical recommendations using evidence-based methods are able to require that randomized trials be available to reach strong conclusions, the IOM committee was convened specifically to assess topics that are of immediate concern yet for which data may just be emerging