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At the cellular level, proteostasis is emerging as a critical factor in the onset and progression of MetS

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Pasetti, [email protected] Present address: Gaelle Noel, Institut Pasteur, Center for Translational Science, Paris, France These authors have contributed equally to this work This article was submitted to Stem Cell Research, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Okawara M, Hashimoto F, Todo H, Sugibayashi K, Tokudome Y

Compared with previous generations, todays youth, due to an earlier average age of puberty (Biro et al., 2010), may have a greater mismatch between the propensity to engage in risk taking (which arises with the onset of puberty) and behavioral inhibition (which is associated with development of the prefrontal cortex)