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Preformed coenzyme forms of B vitamins, including methylcobalamin, offer immediate, direct nutritional support, even for those with genetic differences that impair metabolism of standard B vitamins

Nausea, mild stomach discomfort, and reduced appetite are the most common

doi: 10.3389/fphar.2022.878407 Received 18 February 2022 Accepted 09 May 2022 Published 22 June 2022 Volume 13 - 2022 Edited by Kunlin Zhang, Institute of Psychology (CAS), China Reviewed by Shih-Min Hsia, Taipei Medical University, Taiwan Matthias David, Charit University Medicine Berlin, Germany Updates Copyright 2022 Arip, Yap, Rajagopal, Selvaraja, Dharmendra and Chinnapan

Together, these B vitamins work synergistically to support energy levels, metabolism, mental clarity, and overall wellbeing

The expected and detected masses of the selected compounds are presented in the Supplementary Table 5