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The most common comorbidities that underlie cognitive impairment include pathologic changes associated with cerebrovascular and other concomitant neurodegenerative diseases (e.g., Lewy bodies, TDP-43, and hippocampal sclerosis)

Thiamine (vitamin B1): Metabolism and focus vitamin, especially beneficial for those post-bariatric surgery, or with cognitive decline, diabetes mellitus (improves carbohydrate metabolism), brain fog

Royo et al., 2016)

In a multi-institutional retrospective study of 3,047 cancer patients, weight loss occurring prior to the initiation of systemic chemotherapy, independent of disease stage and patient performance status, was predictive of disease progression and poor prognosis.[2] Cancer cachexia is characterized by an inflammatory state, insulin resistance, and loss of skeletal muscle due to protein breakdown and lipolysis