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Manivannan et al

This site contains many useful tools including the ability to search topics in open SBIR and STTR solicitations, links to the proposal submission site, and access to DSIP Topic Q&A

This includes upregulation of antioxidant enzymes (superoxide dismutase, catalase) that protect against oxidative damage, enhancement of growth factor expression (TGF-, VEGF, PDGF) that supports tissue repair, and suppression of inflammatory gene expression that contributes to chronic skin degradation

The theoretical rationale is strong, supported by decades of immunology research demonstrating its Th1/Treg-promoting effects and the well-established Th2 dominance of eczema

to affect the steroid profile)