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Using an inducible, epidermal-specific c-Jun/JunB double-knockout (DKO*) mouse model that faithfully recapitulates psoriatic skin and arthritis, the authors reveal profound metabolic alterations characterized by reductions in dermal fat and circulating free fatty acids, as well as elevated -hydroxybutyrate [3]

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Mutat Res 531:3780 Blanco MA, Sherman PW (2005) Maximum longevities of chemically protected and non-protected fishes, reptiles, and amphibians support evolutionary hypotheses of aging