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GHRH activates the GHRH receptor (GHRH-R) by stimulating intracellular cAMP levels, resulting in GH secretion (Mayo, 1992)

Donanemab targets accumulation of amyloid beta protein in the brain

On the tissue repair side, BPC-157 upregulates growth hormone receptors on tendon fibroblasts, promotes blood vessel formation through the VEGFR2-Akt-eNOS pathway, and activates the FAK-paxillin pathway for fibroblast migration