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Research from Johns Hopkins Medicine on the gut-brain axis has established bidirectional communication between the gut and brain via the vagus nerve and through neurotransmitter production

10.1016/j.jpba.2018.07.056 8 Centralne Biuro Sledcze Policji (2023)

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18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms

doi: 10.3390/pharmaceutics14122573 41 HarrisonLISkinnerSLMarburyTCOwensMLKurupSMcKaneSet al