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Interestingly this mutation is located in a residue next to the LNCaP prostate cancer cell line mutation Thr878Ala (139, 225), supporting the view that this region in the ligand binding domain of the androgen receptor is very susceptible to mutagenesis in prostate cancer, which may lead to the tumor becoming resistant to hormone-based therapies

Only one subject (4.2%) improved to normal status

By 2035, demand will be supported by the aging population, rising rates of cardiovascular disease, and the growing body of clinical evidence supporting L-Carnitine's role in cardiac function