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9,13 Other mechanisms of hepatotoxicity include the formation of toxic free radicals, such as peroxynitrite, from the reaction of superoxide and nitric oxide, subsequently forming nitrotyrosine adducts inside the mitochondria

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This inevitably results in low IGF-I and high GH that may stray into the acromegaly range (132, 133) and this catabolic state is comparable to prolonged fasting and malnutrition states ( Figure 1E )

These changes are marked by respiratory dysfunction, low coupling efficiency of the mitochondrial ETC, raising electron leakage and increased ROS generation

Purity: 99.88% CAS No.: 56-85-9 Formula: C 5 H 10 N 2 O 3 Molecular Weight:146.15 Storage:Powder -20C, 3 years , 4C, 2 years