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The lack of success at Phase III was attributed to factors such as high baseline immunosuppressive therapy in patients and complex disease mechanisms in SLE, potentially limiting the application of Rituximab as a monotherapy in SLE (119)

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Others is defined as the percentage of cell death that was not rescued by a concomitant inhibition with Fer-1 and zVAD

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Sequences of primers can be found in Supplementary Table S2

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[24] Impaired axonal transport of alpha-synuclein may also lead to its accumulation in Lewy bodies

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