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The used method potentially enables the retrospective evaluation of the acquired data for unknown metabolites by means of a non-targeted approach with high-resolution/high-accuracy full-scan mass spectrometry with additional higher collision energy dissociation experiments

If any step is under-supported or dysregulated, overall detoxification efficiency is compromised

[8] It may seem like common sense to take a supplement to address a deficiency in folate, but not all sources of vitamin B9 are created equally

Mouse plasma was used as a diluent for samples when necessary

These data indicated that cell death was not a prerequisite of PUFA-induced and GPX4-restricted intestinal inflammation in Gpx4 +/IEC mice