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Won JH, Park S, Hong S, Son S, Yu JW

Dietary reference intakes for the antioxidant nutrients: vitamin C, vitamin E, selenium, and carotenoids

showed significantly higher reduced glutathione levels and non-significantly lower uric acid levels in individuals with GS

(2018) demonstrated a gut-brain signaling axis in a mouse model of NEC in which activation of intestinal TLR-4 signaling led to release of high-mobility group box 1 (HMGB1) protein in the intestine, which in turn, promoted activation of TLR-4 on brain microglial cells resulting in accumulation of reactive oxygen species, loss of oligodendrocyte premature cells, dysmyelination, and cognitive impairment

But certain presentations consistently produce faster, more dramatic before and after outcomes