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10.3390/biomedicines1108221237626709 127 Colantonio LD, Reynolds RJ, Merriman TR, et al

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That is why its effect in studies extends far beyond the gastrointestinal tract, where it was originally discovered

The genome-wide CRISPR screen was performed in HEK293 cells using the Brunello library 23 encompassing ~77,000 guide RNAs (sgRNAs) against ~19,000 human genes (4 sgRNas per gene) (Fig