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Description

NTZ effects were dose-dependent, where the higher dose was more efficient and closer to the effect of NAC or 4-PBA

Retrieved from Hoffman, B

10.1016/j.mito.2019.06.002 Mitochondrion 264 WilsonD

Waring MJ

For instance, P115 and GRASP65 trigger apoptosis via the ERK/p53/PUMA pathway or Fas-mediated signaling, respectively, whereas Bruce and GAAP decrease apoptosis via caspase-9, Smac and p53 inhibition, and Ca 2+ signaling downregulation [93]