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While initially proposed to have HAT activity 23 , previous work 24,25 , along with our data shown here, show that eukaryotic HAT-like domains cannot bind acetyl-CoA, classifying them as pHATs of unknown function

Frhlich, H

Through a comprehensive analysis of patients who experienced stay-up-late and the establishment of sleep deprivation animal models, we have identified that serum serine levels were also closely related to AMH levels in POI, suggesting that serine deficiency may be a common cause for various POI 62,79

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