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Human platelets express Toll-like receptor 3 and respond to poly I:C

This will benefit our understanding of the aetiologies involved in ADs and permit the development of therapeutic strategies that aim to improve intestinal barrier integrity to help tackle the burden caused by inflammatory diseases

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N Engl J Med 343:180184 Tepel M, van der Giet M, Statz M, Jankowski J, Zidek W (2003) The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure

With the advent of endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic cholangiography (PTC) in the 1970s, the characteristic beaded or pruned tree cholangiographic appearance obviated the need for exploratory surgery to diagnose PSC and resulted in its increased recognition (Wiesner & LaRusso, 1980