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Shukitt-Hale B, Denisova NA, Strain JG, Joseph JA

The combination of BSO+L-PAM achieved synergistic cytotoxicity (combination index number (CIN) 0.7) and induced 24 logs of cell kill in all nine MM cell lines including the eight lines established at progressive disease (PD) after therapy (U266, OPM-2, NCI H929, KMS-12-PE, EJM, TX-MM-030h, MM.1S and MOLP-2), 25 which include lines with cytogenetic profiles associated with a poor prognosis (Figure 1b)

Why GHK-Cu has shorter stability Most peptides remain stable in reconstituted form for 4-6 weeks refrigerated

During invasion, cells degrade or remodel the surrounding extracellular matrix and migrate through the tissue boundary (Kermorgant et al, 2001)