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Landscapes Health & Medical Sciences (AREA) Life Sciences & Earth Sciences (AREA) Veterinary Medicine (AREA) Animal Behavior & Ethology (AREA) General Health & Medical Sciences (AREA) Public Health (AREA) Epidemiology (AREA) Chemical & Material Sciences (AREA) Medicinal Chemistry (AREA) Pharmacology & Pharmacy (AREA) Dermatology (AREA) Gerontology & Geriatric Medicine (AREA) Birds (AREA) Engineering & Computer Science (AREA) Bioinformatics & Cheminformatics (AREA) Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA) General Chemical & Material Sciences (AREA) Organic Chemistry (AREA) Chemical Kinetics & Catalysis (AREA) Gastroenterology & Hepatology (AREA) Immunology (AREA) Proteomics, Peptides & Aminoacids (AREA) Cosmetics (AREA) Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA) Abstract A topical composition for application to aging skin, comprising an effective amount of S-acyl glutathione derivative of formula (I) wherein R 1 consists of an unsaturated or saturated C 16 group and R 2 is a hydrogen, aliphatic or aromatic acyl group

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Cozza G, Rossetto M, Bosello-Travain V, Maiorino M, Roveri A, Toppo S et al (2017) Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: the polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center

doi: 10.1007/s10439-014-1005-9 44 ShmakovaATsimailoIKozhevnikovaYGrardLBoutboulDOksenhendlerEet al