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Gastroenterology 118 , 10941105 (2000)

However, several fundamental gaps remain

In addition, in fatal cases of HS, there is extensive bleeding and necrosis of the intestine [19]

FIGURE 2 3.1 Mechanisms of ferroptosis 3.1.1 Iron overload is an important cause of ferroptosis Iron overload is a pivotal component in the occurrence of ferroptosis