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Similar content being viewed by others Introduction Reactive oxygen species (ROS) are oxygen-containing reactive chemicals including superoxide (O 2 ), hydroxyl radical (OH), hydrogen peroxide (H 2 O 2 ), and singlet oxygen ( 1 O 2 ) [1]

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For instance, in Cogans syndrome the immunoglobulin G (IgG) immunoglobulins have an affinity for a supporting protein in the sensory epithelia of the inner ear Density-Enhanced Protein tyrosine phosphatase-1 (DEP-1/CD148) as well as connexin 26 that results in sensorineural hearing loss in mice [58]

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