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However, 80% of such mice displayed hindlimb paralysis and died with 8 weeks, therefore preventing us from proceeding further

Bulbena A, Baeza-Velasco C, Bulbena-Cabr A, Pailhez G, Critchley H, Chopra P, Mallorqu-Bagu N, Frank C, Porges S

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Researchers have proposed that this protective activity may be linked to Semaxs influence on neurotrophic signaling, though the precise mechanisms are still an active area of investigation