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Those with pre-existing conditions such as irritable bowel syndrome (IBS), functional dyspepsia, or gastritis may be more prone to experiencing stomach upset from supplements generally, including B12 preparations

For consistency across studies, document solvent, concentration, storage temperature, freezethaw cycles, and light exposure conditions in experimental records

As described by Cant et al

While advanced drug delivery systems or modified peptide formulations are being explored in general peptide research to extend half-lives, these are not typically available for unmodified AOD-9604 in 2026