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Nat Biotechnol 42:293304 Harigae H, Takahashi S, Suwabe N, Ohtsu H, Gu L, Yang Z, Tsai FY, Kitamura Y, Engel JD, Yamamoto M (1998) Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells

These models can be used to explore the pathogenesis of ALD at different stages or different degrees of severity, and provide research tools for discovering new drug targets with potential for the treatment of ALD

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The mucus layer, mainly composed of mucin 5AC (Muc5AC) and mucin 5B (Muc5B) secreted by goblet cells, determines the rheological properties of mucus, which provide the structural basis for cilia-mediated clearance (21)