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Conclusions The combined effects of exercise and polyphenol supplementation offer a promising, non-pharmacological approach for managing depression and enhancing brain function

Superoxide combines with NO to form peroxynitrite that oxidizes BH 4 and destabilizes eNOS to produce more superoxide 22, 24, 25 thus, further enhancing the development of oxidative stress

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Detection of Antioxidant Enzyme Activities Ascorbate peroxidase activity was detected as described in Dehydroascorbate reductase (DHAR) activity was determined as described in Glutathione reductase activity was detected as described in Preparation of Nonprotein Thiol Extracts The alga (0.2 g of DT) was frozen in liquid nitrogen and homogenized in a mortar with a pestle and extracted by addition of 1.2 ml of 0.1% (w/v) trifluoroacetic acid (TFA)6.3 mM diethylenetriaminepentaacetic acid (DTPA)