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Cells with developed resistance to heavy-metalbased cytostatics have increased expression of MTs

Cardiovascular Events: In the past, some studies have associated the use of Diane 35 with risks of events such as heart attack and stroke in women with added risk factors like smoking or hypertension

Calcium Calcium ions are important intracellular signals that regulate a number of physiological processes, including neuronal gene expression, neuronal secretion of neurotransmitters into synapses, and synaptic plasticity (reviewed in 60)

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Another small molecule, HET0016, inhibits the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite of arachidonic acid, and demonstrates neuroprotective effects after ICH (209)