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Bning Journal: Molecular therapy : the journal of the American Society of Gene Therapy Journal ranking: Q1 Key takeaways: Tropism-modified AAV vectors with novel receptors significantly improve cutaneous gene therapy by increasing cell entry efficiency and targeting v8 integrin, overcoming safety concerns.

Lipoic acid also protected liver from oxidative stress-induced liver injury in methotrexate-treated rats through the activation of Nrf-2 pathway and other anti-inflammatory pathways (37)

This gene modulation capability extends to shifting gene expression in COPD lungs from a destructive state to one of healthy remodeling, showcasing its broad therapeutic potential 13

IV treatments may show visible improvements in 24 weeks

10.1016/j.jri.2022.103676 5 BaiR