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Description

Activation of p53 by scaffold-stabilised expression of Mdm2-binding peptides: visualisation of reporter gene induction at the single-cell level

doi: 10.1007/s11356-020-07651-5

The exact mechanism of action of SIRT on preventing virus replication is not known

All these perturbations are implicated in mitochondrial dysfunction, hence strategies to mitigate this may pose an important therapeutic avenue

The same defensive/damage repair mechanism is also manifested in cancer cells, and an amplified capability to repair DNA by tumour cells is also linked with a greater incidence of resistance to anti-cancer agents